The overall goal of our research program is to improve outcomes for children through the delivery of evidence-based, personalized care. Towards this, we aim to find quantifiable markers that give insight into the underlying disease mechanisms and help with a diagnosis and treatment.
We use a bedside-to-bench approach, with initial ‘discovery’ studies done on patient samples and follow-up mechanistic studies employing in vitro and in vivo experimental systems to tease the markers of inflammation apart from the drivers. We have a particular interest in two groups of rheumatic diseases: primary chronic systemic vasculitis and autoinflammatory syndromes.
We are grateful for past and present research project funding from the Canadian Institute of Health Research, National Institutes of Health, Canadian Foundation for Innovation, Rare Disease Foundation, BC Lung Foundation, and BC Children’s Hospital Foundation.
