Adenosine deaminase 2 is an extracellular growth factor and enzyme that breaks down the molecules adenosine and 2’-deoxyadenosine. A “deficiency in ADA2 (DADA2)” causes abnormalities in organs, tissues, blood vessels and/or immune cells, which can be life threatening. We measure ADA2 enzymatic activity in plasma or sera and compare to in-house established normative ranges for healthy children. Reference: Bowers et. al. Pediatr. Rheumatol. Online. J. (2020) 18(1): 54.