Since 2012, Dr. Brown has been the co-lead of the Pediatric Vasculitis (PedVas) Initiative, an international study on pediatric chronic systemic vasculitis that has collaborators in more than 40 centres worldwide.

PedVas has resulted in the establishment of the single largest pediatric vasculitis data and sample repository. With this one-of-a-kind resource, Dr Brown and her colleagues have established a program of basic, clinical and translational research to improve current phenotypic classification criteria and clinical scoring tools to assess disease activity and damage. 

Our research has contributed some of the first pediatric-specific evidence on the biology of the disease and the utility of biomarkers for improved disease severity assessment and prediction of overall and organ-specific health outcomes.