All – Brown Lab

Comparing rituximab and cyclophosphamide in induction therapy for childhood-onset ANCA-associated vasculitis: An ARChiVe registry-cohort study.

Gagne S, Sivaraman V, Bosman E, Klamer B, Brown KL, Morishita KA, Cabral DA on behalf of the PedVas Investigators Network.
(2024) Submitted

Editorial: Innate immunity in Vasculitis.

De Souza AWS, Ooi JD, Misra DP, Zhong Y, Brown KL.
(2024) Frontiers in Immunology 15:1432069. PubMed

Evaluating renal disease in pediatric-onset anti-neutrophil cytoplasmic antibody-associated vasculitis: disease course, outcomes, and predictors of outcome

Toor KK, Chen A, Cabral DA, Mammen C, Bosman E, Shen Y, Bone J, Noone D, Al-Abadi E, Benseler S, Berard R, Bohm M, Charuvanij S, Cook K, Dancey P, Deepak S, Duffy C, Eberhard B, Elder M, Foell D, Gerstbacher D, Heshin-Bekenstein M, Huber A, James K, Kim S, Klein-Gitelman M, Martin N, McErlane F, Moorthy L, Myrup C, Riley P, Shenoi S, Tanner T, Tarvin S, Yeung R, Brown KL, Morishita KA
(2024) Arthritis & Rheumatology. In review.

Predictive utility of ANCA positivity and antigen specificity in the assessment of kidney disease in pediatric onset small vessel vasculitis.

Mann S, Bone J, Bosman E, Cabral DA, Morishita KA, Brown KL on behalf of the PedVas Investigator Network
(2024) Rheumatic and Musculoskeletal Diseases (RMD) Open. 10(2):e004315 PubMed

Behcet’s Syndrome – Recent advances to aid diagnosis

Akbaba TH, Ekici M, Çolpak Aİ, Brown KL, Karadağ Ö, Balci-Peynircioglu B.
(2023) Clinical and Experimental Medicine. 23(8):4079-4090. PubMed

Anti-LAMP-2 Antibody Seropositivity in Children with Primary Systemic Vasculitis Affecting Medium- and Large-Sized Vessels.

Akbaba TH, Toor KK, Mann SK, Gibson KM, Alfaro GA, Balci-Peynircioglu B, Cabral DA, Morishita KA, Brown KL on behalf of the PedVas Investigator’s Network.
(2024) International Journal of Molecular Sciences 25(7):3771. PubMed

Pathogenic variant c.1052T>A (p.Leu351Gln) in adenosine deaminase 2 impairs secretion and elevates Type I IFN responsive gene expression

Bowers SM, Sundqvist M, Dancey P, Cabral DA and Brown KL.
(2022) Frontiers Immunology. 13: 995191. doi: 10.3389/fimmu.2022.995191. PubMed

Publications

Comparing rituximab and cyclophosphamide in induction therapy for childhood-onset ANCA-associated vasculitis: An ARChiVe registry-cohort study.

Editorial: Innate immunity in Vasculitis.

Evaluating renal disease in pediatric-onset anti-neutrophil cytoplasmic antibody-associated vasculitis: disease course, outcomes, and predictors of outcome

Predictive utility of ANCA positivity and antigen specificity in the assessment of kidney disease in pediatric onset small vessel vasculitis.

Behcet’s Syndrome – Recent advances to aid diagnosis

Anti-LAMP-2 Antibody Seropositivity in Children with Primary Systemic Vasculitis Affecting Medium- and Large-Sized Vessels.

Hyaluronan promotes intracellular ROS production and apoptosis in TNFα-stimulated neutrophils

Elevated adenosine deaminase 2 (ADA2) enzyme activity at the onset of chronic Graft-versus-Host Disease in children

HLA-DBP1 is associated with ANCA-associated vasculitis in children

Pathogenic variant c.1052T>A (p.Leu351Gln) in adenosine deaminase 2 impairs secretion and elevates Type I IFN responsive gene expression

Brown Lab

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